13 timmar sedan · Medivir erhöll en betalning på 1 miljon USD efter underteckn-andet av avtalet, detta kommer följas av ytterligare 1,5 miljoner USD när IGM inkluderar birinapant i kliniska fas I-studier. Avtalet berättigar dessutom Medivir till milstolpeersättningar och royalty.

The agreement provided Medivir with a payment of USD 1 million after signing, which is to be followed by an additional USD 1.5 million when IGM includes birinapant in phase I clinical trials. Furthermore, the agreement entitles Medivir to milestone payments up to a total of approximately USD 350 million , given that birinapant is successfully

Medivir är ett läkemedelsbolag. Bolaget utvecklar läkemedel med fokus på cancersjukdomar med stort medicinskt behov. Bolaget satsar på indikationsområden där tillgängliga behandlingsmetoder är begränsade eller där de saknas. Nov 9, 2016 The acquisition includes remetinostat, a skin-directed histone deacetylase ( HDAC) inhibitor, and birinapant, a bivalent second mitochondrial Birinapant, a SMAC mimetic, has been out-licensed for development in combination with IGM antibodies for the treatment of solid tumors. Contact Information. Oct 10, 2019 Medivir provides birinapant and will be afforded full access to all reports from the study under its Cooperative Research and Development Nov 2, 2016 The acquisition includes remetinostat, a skin-directed HDAC inhibitor, and birinapant, a bivalent SMAC mimetic, and all intellectual property and 21 hours ago STOCKHOLM, April 20, 2021 /PRNewswire/ -- Medivir AB (Nasdaq Stockholm: Birinapant, a SMAC mimetic, is exclusively outlicensed to IGM Birinapant (TL32711), a bivalent Smac mimetic, is a potent antagonist for XIAP and cIAP1 with Kds of 45 nM and less than 1 nM, respectively. Birinapant Apr 6, 2021 Birinapant, a SMAC mimetic, is exclusively outlicensed to IGM Biosciences ( Nasdaq: IGMS) to be developed in combination with IGM-antibodies Dec 16, 2020 An agreement between Medivir AB and TetraLogic Pharmaceuticals, Birinapant was originally acquired by Medivir from TetraLogic in 2016.

Medivir birinapant

Nettoomsättningen uppgick till 13,9 (8,7) MSEK. Medivir förvärvade birinapant från TetraLogic 2016. Det ursprungliga avtalet mellan Medivir och TetraLogic innefattade bland annat milstolpesersättningar med förutbestämda belopp samt royalty-skyldigheter till TetraLogic om och när Medivir utvecklar, marknadsför eller utlicensierar birinapant vidare. Birinapant (formerly TL 32711) is a synthetic, small molecule, bivalent mimetic of the second mitochondrial-derived activator of caspase (also called SMAC or Birinapant - Medivir AB - AdisInsight Either you have JavaScript disabled or your browser does not support Javascript . Medivir är ett läkemedelsbolag. Bolaget utvecklar läkemedel med fokus på cancersjukdomar med stort medicinskt behov.

31 Mar 2021 Birinapant, a SMAC mimetic, is exclusively outlicensed to IGM Biosciences ( Nasdaq: IGMS) to be developed in combination with IGM-antibodies

Notable ongoing projects. Remetinostat, HDAC inhibitor for Cutaneous T cell lymphoma. Birinapant, SMAC mimetic for solid tumours.

21 hours ago STOCKHOLM, April 20, 2021 /PRNewswire/ -- Medivir AB (Nasdaq Stockholm: Birinapant, a SMAC mimetic, is exclusively outlicensed to IGM

Our research and development are based on our extensive expertise in protease inhibitor design and nucleoside/nucleotide science. Science working wonders. 2021-01-12 Medivir acquired birinapant from TetraLogic in 2016. The original agreement between Medivir and TetraLogic included milestone payments with predetermined amounts as well as royalty obligations to Nya data från fas I-studien av birinapant i kombination med Keytruda® presenterades vid ASCO:s årsmöte. Stockholm — Medivir AB (Nasdaq Stockholm: MVIR) meddelar idag att nya data från fas I-studien av birinapant i kombination med pembrolizumab (Keytruda®) har presenterats på en muntlig session den 2 juni vid årsmötet för American Society of Clinical Oncology (ASCO) i Chicago. 2017-08-18 Stockholm — Medivir AB (publ) (Nasdaq Stockholm: MVIR) meddelade idag att bolaget har ingått ett exklusivt licensavtal som ger IGM Biosciences, Inc. (Nasdaq: IGMS) de globala och exklusiva rättigheterna att utveckla birinapant, ett SMAC-mimetikum i klinisk utvecklingsfas som binder till och bryter ned hämmare av apoptosproteiner (IAP), vilket leder till celldöd (apoptos) i tumörceller.

av Medivirs kliniska projekt framskrider enligt plan och under kvartalet har ytterligare en klinisk kombinationsstudie med birinapant inletts, MEDIVIR: TECKNAT LICENSAVTAL FÖR BIRINAPANT MED IGM. STOCKHOLM (Nyhetsbyrån Direkt) Medivir har ingått ett exklusivt licensavtal som ger Medivir erhåller en betalning på 1 miljon dollar efter undertecknandet av avtalet, följt av ytterligare 1,5 miljoner dollar när IGM inkluderar birinapant i kliniska fas Medivir erhåller en betalning på 1 miljon USD efter undertecknandet av avtalet, följt av ytterligare 1,5 miljoner USD när IGM inkluderar birinapant i kliniska fas Villkoren i avtalet berättigar dessutom Medivir till milstolpebetalningar upp till totalt cirka 350 miljoner USD, givet att birinapant framgångsrikt Medivir har flera forskningsrelaterade milstolpar under 2019. Bolagets projekt birinapant utvärderas för närvarande i en pågående klinisk fas Senaste nyheterna om aktien Medivir (MVIR B). Analyser, rekommendationer & riktkurser för Medivir aktien. Medivir: License Deal for Birinapant. Redeye Redeye har intervjuat Medivirs vd, Yilmaz Mahshid, till följd av nyheten om licensavtalet för Birinapant med IGM Biosciences värt upp till 350m USD. Kliniska prövningar för Medivir. Kliniska prövningar sponsrade av Medivir Dose-escalation Study of Birinapant and Pembrolizumab in Solid Tumors. Medivir / Birinapant / Birinapant. igår 16:40.
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Stockholm, Sweden — Medivir AB (Nasdaq Stockholm: MVIR) today announced safety and efficacy data following an interim analysis of phase I data from the ongoing phase I/II study of birinapant in combination with MSD’s anti-PD-1 therapy, Keytruda® (pembrolizumab), in patients with advanced solid tumors who have exhausted available treatment options.

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\\- IGM to Develop Birinapant in Combination with IGM-8444 for the Treatment of Solid Tumors -MOUNTAIN VIEW, Calif., Jan. 11, 2021 (GLOBE NEWSWIRE) -- IGM Biosciences, Inc. (Nasdaq: IGMS) today

In addition, the The agreement provided Medivir with a payment of USD 1 million after signing, which is to be followed by an additional USD 1.5 million when IGM includes birinapant in phase I clinical trials.

2021-02-10 · Collaborations and partnerships are important parts of Medivir's business model, and the drug development is conducted either by Medivir or in partnership. Birinapant, a SMAC mimetic, is

Birinapant is a SMAC mimetic that was acquired from TetraLogic Pharmaceuticals Corporation (TetraLogic) in 2016 and has since then been developed by Medivir.

The original agreement between Medivir and TetraLogic included milestone payments with predetermined amounts as well as royalty obligations to About birinapant Birinapant is a SMAC mimetic that was acquired from TetraLogic Pharmaceuticals Corporation (TetraLogic) in 2016 and has since then been developed by Medivir. Medivir acquired birinapant from TetraLogic in 2016. The original agreement between Medivir and TetraLogic included milestone payments with predetermined amounts as well as royalty obligations to TetraLogic if and when Medivir develops, markets or out-licenses birinapant further. MOUNTAIN VIEW, Calif., Jan 11, 2021 (GLOBE NEWSWIRE via COMTEX) -- MOUNTAIN VIEW, Calif., Jan. 11, 2021 (GLOBE NEWSWIRE) -- IGM Biosciences, Inc. (Nasdaq: Birinapant is a SMAC mimetic that was acquired from TetraLogic Pharmaceuticals Corporation (TetraLogic) in 2016 and has since then been developed by Medivir.